Always heed the Prophecy. Even if you can't do anything about it, you should definitely heed it. Heeding in general is an all round good idea. Take a few extra levels in heeding, just in case.
Transcript
Yoda: The Jedi's fault all of this is. Heed the Prophecy we should have.
Yoda: I'm going to go into exile and meditate on the failures of the Jedi until I come up with an answer.
Obi-Wan: We need to rebuild the Jedi and restore order to the Republic.
Yoda: Come on. Let's be hermits together!
Obi-Wan: That's... not how hermits work...
Yoda: You're a stubborn boot-licking sycophant! I'm doing what I want to do, not what anyone tells me!
{beat, Obi-Wan stares at Yoda}
Obi-Wan: Fine then.
Obi-Wan: I'll take the boy as far away from Alderaan as possible.
Padmé: {aside} Give him my underwater oxygen extraction apparatus and grappling hook!
Yoda: Good! Keep them apart that will. This brother and sister will never have to meet each other!