A good GM will tailor the challenges to the characters.

By "tailor", we mean make the challenges able to exploit any weaknesses the characters have.

By "weaknesses", we mean any feature that pretty much applies to any human (or alien) being.

And by "challenges" we mean deadly threats.

Transcript

Anakin: I look around to see where the sound came from.
Pete: Okay, there are... <roll> fourteen winged, slimy creatures following you down the corridor.
{Anakin draws his laser sword}
[SFX]: Whooom!
Anakin: Quick! To the exit!
Pete: Another... <roll> nine noxious nasties drop from the ceiling in front of you.
[SFX]: Whooom!
Padmé: Where are the robots?
[SFX]: Whooom!
[SFX]: Kssssh!
[SFX]: < bedoop bak-jing >
C-3PO: We're right behind you!
Anakin: Come on, quick! Before you get swarmed!
Pete: The denizens are hungry. They're completely ignoring the droids.
[SFX]: Whooom!
Anakin: Of course. How convenient.
[SFX]: < doop boop bleep squee ding >
R2-D2: Not my fault you're made of meat.
C-3PO: Yeah!